Estimation of dietary 14C dose coefficient using 13C-labelled compound administration analysis

Monitoring the Level of 14C-Labelled Selegiline Following Oral Administration

BACKGROUND Selegiline [(-)-deprenyl] is widely used for the treatment of Parkinson's disease in humans. OBJECTIVE Time-dependence of tissue distribution of selegiline following per os administration to rats. METHOD Oral administration of radiolabeled selegiline to rats resulted in a pattern of tissue distribution similar to that following intraperitoneal injection. Analyses were done using ...

Metabolism of 14C-labelled alphaxalone in man.

The metabolism of 14C-labelled alphaxalone, dispensed as Althesin, was studied in normal patients, patients with obstructive jaundice and patients with chronic renal disease and anuria. The radioactive label was removed rapidly from the plasma following i.v. administration. The major portion of the label was excreted in the urine. In patients with normal renal function 14C-labelled alphaxalone ...

analysis of ruin probability for insurance companies using markov chain

در این پایان نامه نشان داده ایم که چگونه می توان مدل ریسک بیمه ای اسپیرر اندرسون را به کمک زنجیره های مارکوف تعریف کرد. سپس به کمک روش های آنالیز ماتریسی احتمال برشکستگی ، میزان مازاد در هنگام برشکستگی و میزان کسری بودجه در زمان وقوع برشکستگی را محاسبه کرده ایم. هدف ما در این پایان نامه بسیار محاسباتی و کاربردی تر از روش های است که در گذشته برای محاسبه این احتمال ارائه شده است. در ابتدا ما نشا...

The Use of 13C in the Synthesis of Double Labelled Precursors

Discovery of 13C NMR and its application in the biosynthetic pathways prompted the synthesis of several 13C labelled precursors. To investigate the metabolism of phenyllactic acid in the Solanaceae family, the double labelled acid was synthesized from barium carbonate (13C) and sodium syanide (13C)

Metabolism of 14C-ring-labelled paracetamol in humans.